A restricted access barrier system (RABS) provides an enclosed, but not closed, environment meeting defined cleanroom conditions using a rigid-wall enclosure and air overspill to separate its interior from the surrounding environment.
Active RABS: integral HEPA-filtered air supply
Passive RABS: air supply by ceiling mounted HEPA-filters.
Open RABS. Where there are vents in the barrier that allow air to move from the grade A to the grade B area.
Source: GMP Draft Annex 1
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